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Identification and verification of hub genes associated with ferroptosis in ischemia and reperfusion injury during renal transplantation

Additionally, curcumin modulates Sirt1-Foxo1 signaling and enhances PI3K-Akt activity, leading to restored Akt phosphorylation, decreased pro-apoptotic signaling, and improved cellular antioxidant defenses

Heat shock chaperone proteins such as Hsp70 carry out key functions in the repair of cellular injury including reversal of protein misfolding that occur due to oxidative damage

doi: 10.1016/j.cmet.2014.10.006 68 KoethR

Lifestyle Modifications:Regular exercise, adequate sleep, and stress reduction can positively influence mitochondrial health and GSH levels

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