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In controlled rat models, BPC-157 has demonstrated the capacity to completely counteract amphetamine-induced toxicity, reverse neuroleptic-induced catalepsy (often triggered by haloperidol), and mitigate the life-threatening cascade of serotonin syndrome induced by excessive serotonin precursor availability

doi:10.1093/humupd/dmt023

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The translocation of these noxious metabolites into circulation can induce oxidative stress and systemic inflammation, subsequently aggravating renal inflammation and fibrosis