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Calcineurin inhibitors (CNIs), the cornerstone of immunosuppression in liver transplant recipients, are a significant contributor to worsening pre-existing diabetes and contributing to development of PTDM

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Therefore, when estimated assuming 50% additivity, the HRs were 0.73 (95% CI 0.620.87) for MACE, 0.53 (95% CI, 0.410.70) for HHF, and 0.51 (95% CI, 0.380.68) for CKD progression

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92 Thus, aspartate is a limiting factor for growth under hypoxic conditions

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