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The glorified (and apparently exaggerated) results of the EPIC Trial, about which we have written several articles, were announced in this same seemingly unethical manner in three press releases (one each from the three lead researchers), within days of the EPIC trial's end in March 2015

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As an inhibitor of NRF2, Keap1 recognizes and binds to the ETGE and DLG motifs of NRF2 via its Kelch repeat domain, thereby continuously suppressing and promoting the degradation of NRF2 [87]

CYP2E1 induction increases with repeated high-dose alcohol exposure and contributes significantly to ethanol clearance in individuals with alcohol use disorder (AUD)