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secondly, relative to other organs, the brain has lower levels of ROS scavenging enzymes and thirdly the brain is 60% fat a high proportion of which is unsaturated fatty acids that are highly susceptible to lipid peroxidation

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References [1] Mssig K, Knle A, Suberlich AL, et al

Its gastroprotective effects involve upregulation of EGF receptor signalling and prostaglandin pathways in GI mucosa, explaining its longstanding use as a gastric mucosal protective agent in preclinical ulcer and colitis models