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5-Amino-1MQ is a small-molecule compound and selective inhibitor of NNMT (Nicotinamide N-methyltransferase), an enzyme involved in regulating NAD+ metabolism and one-carbon pathway signalling

2017 May 1;117(5):1844-1846 Schultz ST, Gould GG

Elevated NNMT is linked to: Reduced NAD+ availability Slower mitochondrial function Increased fat storage efficiency Higher risk for insulin resistance By reducing NNMT activity, 5-Amino-1MQ allows the body to maintain higher NAD+ levels, which can support better mitochondrial performance, improved fat oxidation, and more balanced energy metabolism

N Engl J Med 2021;385:896907.ArticlePubMed 52

Only after three months of daily injections will all the abnormal cells have been replaced by healthy cells

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