USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice
The levels of microplastics in aquatic environments are diverse, such as 2.46 particles/m 3 in the Northeast Atlantic Ocean 7 , 0.0032 to 1.18 particles/m 3 in the Ross Sea (Antarctica) 8 , 0.028 particles/m 3 in the Tamar Estuary, UK 9 , 300 ng/mL in the North Pacific subtropical gyre 10 , and high abundances and concentrations have been found in polluted areas such as 228 particles m 2 in the Coastline of Qatar Gulf 11 , 324 particles/m 3 or 64,812,600 particles/km 2 in the Israeli Mediterranean coastal waters 12 , and average concentrations of 1.56 1.64 and 5.51 9.09 mg/L in lakes and wetlands 13
In a study, the expression levels of peroxisome proliferator-activated receptor-gamma (PPAR-) and peroxisome proliferator-activated receptor-alpha (PPAR-) genes that were elevated in diabetic rats, attenuated in okra-treated rats (Majd et al., 2018)
Diurnal fluctuation and pharmacological alteration of mouse organ glutathione content
Moreover, the authors extended this mechanism to senescent cancer cells and demonstrated that these cells are more efficient than immunogenic cell death to induce immune system protection against tumor relapse
& Bohmann, D
