Septerna Sector: GPC Septerna R-targeted oral small molecule drug discovery, including GLP-1, GIP, and glucagon receptors HQ: South San Francisco, CA Year Founded: 2019 (under the name GPCR NewCo, Inc.)
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BIA allows for repeated measures at low cost, for instance, when weight reduction trajectories are high and muscle loss is more likely
New formulations use protective technologies that allow the medication to survive the digestive process and be absorbed effectivelythough with some important requirements around timing and dosing
This recommendation is based on compelling evidence: an early-responder analysis showed that 93.4% of patients who failed to meet the 16-week threshold were also unable to achieve a substantial (10%) weight reduction after a full year of treatment