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These interactions may not only affect how well the body absorbs B12 but also how it metabolises and utilises the vitamin, potentially leading to an increase in discomfort post-injection

These are usually mild and go away over time

Its the subject of ongoing studies

Bacterial fermentation creates AdoB 12 and MeB 12 , which are converted to cyanocobalamin by the addition of potassium cyanide in the presence of sodium nitrite and heat

There are no reported risks associated with large doses of B12, since the vitamin is water soluble and excess amounts are flushed out of the system

[124] Other causes of B 12 malabsorption include bariatric surgery, pancreatic insufficiency, obstructive jaundice, tropical sprue, celiac disease, inherited intrinsic factor deficiency, and radiation enteritis affecting the distal ileum