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Net: the oral wave is not just theoretical anymoreregulators are approving it, and fast Within the oral Phase 3 set, the bulk of late-stage activity clusters around: the oral semaglutide franchise (diabetes and weight management), and orforglipron (Foundayo), which has now set a competitive standard for convenience by positioning itself as a pill with no food/water restrictions

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For example, in aged Long Evans rats (15 months), daily administration of CBD at a dose of 10 mg/kg for 10 weeks improved splenic leukocyte function and enhanced systemic antioxidant defense

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Beyond these systemic benefits, evidence now suggests that GLP-1 receptor activation has direct effects on hepatocytes, contributing to reductions in steatosis, inflammation, and fibrosis