Anestl K, Arnr ES (2003) Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine
Citrus fruits, berries, peppers, and leafy greens provide dietary vitamin C
Brunelli L, Caiola E, Marabese M, Broggini M, Pastorelli R (2014) Capturing the metabolic diversity of KRAS mutants in non-small-cell lung cancer cells
Secondly, the low level of serum GPx in obese patients and the low-serum Se concentrations, associated with the onset of signs of metabolic syndrome, may be related to the presence of a predisposing state to atherosclerosis manifested by increased consumption of antioxidants by radical interaction [19, 62]
A 2025 human pilot study reported no adverse cardiac, hepatic, or renal effects at IV doses of 10-20mg
Glutathione deficiency in older adults appears to stem from impaired synthesis, driven both by reduced availability of precursor amino acids (cysteine and glycine) and, per more recent research, by lower expression of the enzymes needed to produce glutathione