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Briere DA, et al

Figure 4 4.2 Classical and non-classical pathways of ferroptosis in COPD Ferroptosis is regulated by two distinct pathwaysclassical and non-classicalboth of which are dysregulated in COPD

Furthermore, studies have indicated the effect of ROS on CD4 + T cells, where NOX-2-derived ROS can promote the differentiation of T cells from Th17 to Th2 phenotype [50]

This research area traces directly back to Pickarts original liver-tissue findings, since the same signaling behavior that prompted aged liver cells to behave more like younger cells has since been examined across skin and connective tissue models as well

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