The SURPASS 1 trial compared increasing doses to evaluate dose response
DEXA scans are becoming more widely available and affordable
Retatrutide (LY3437943) is a synthetic peptide composed of 39 amino acids, engineered with a C20 fatty diacid moiety that extends its half-life to approximately six days and supports once-weekly administration in research settings
Emphasize smoking cessation Manage BP, lipids using diabetes thresholds Screen for diabetes Encourage maintenance of healthy weight Slightly higher risk of overall cancer development Emphasize need for malignancy screening, especially cervical and colorectal cancer Discuss reproductive health Assess bone health Risk of vitamin D deficiency due to sun avoidance and decreased bone density from glucocorticoid use and inflammation Assess mental health Anxiety and depression is commonly seen in patients with lupus
NICE recommends tirzepatide for type 2 diabetes An estimated 180,000 people could benefit from a decision by NICE to recommend a new treatment option for adults with difficult-to-manage type 2 diabetes, alongside diet and exercise
S.-licensed providers who evaluate treatment options and determine if compounded GLP-1/GIP medications are appropriate
