Studies show by inhibiting NNMT, the 5 amino compound prevents unnecessary methylation of nicotinamide, thus preserving NAD+ for energy metabolism
It can be found naturally in certain animal products, but it is also commonly added to foods or taken as an oral supplement or injection
Because vitamin B12 is water-soluble, any excess is safely excreted through urine, making ongoing treatment safe under proper supervision
Shaking the vial after mixing
Targeted Treatment : Injections allow health care professionals to deliver precise amounts that match their needs, thus achieving the best results
Key metabolic effects include: Enhanced lipolysis through activation of fat breakdown pathways independent of growth hormone receptors Suppressed lipogenesis reducing conversion of non-fat substrates into stored fat Increased fat oxidation and energy expenditure in multiple species models No adverse effects on insulin sensitivity or glucose metabolism, unlike full-length growth hormone Independence from IGF-1 Signaling A critical distinction of AOD-9604 is its lack of IGF-1 pathway activation: No measurable changes in serum IGF-1 levels in human clinical trials Absence of growth-promoting effects on tissues No impact on blood glucose regulation or insulin resistance Avoidance of typical growth hormone side effects including edema and tissue overgrowth Metabolic Pathway Modulation Research indicates AOD-9604 influences energy metabolism through multiple mechanisms: Increased whole-body fat oxidation rates in animal models Enhanced metabolic rate without stimulant-like effects Potential modulation of uncoupling proteins in adipose tissue Effects on lipid metabolism that persist beyond plasma clearance Critical Mechanistic Gap: Despite extensive research, the primary receptor target for AOD-9604 remains unidentified
