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This is a 6.75 fold increased in percent weight loss from highest dose to placebo, compared to the 5.9 fold increase seen in the STEP-1 trial
Despite activating more receptors, Retatrutide does not produce dramatically worse tolerability than Tirzepatide
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They are ideal for patients looking for sustainable, ongoing support rather than a quick fix
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Deaths ( n = 60) in total occurred in the study, 25 (3%) in the tirzepatide arms and five (4%) in the insulin glargine arm (HR, 0.70
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