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Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

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10.1016/j.redox.2016.10.019 113 ZhangC

After a meal, insulin secretion is stimulated quickly and considerably in order to maintain plasma glucose concentrations within a narrow physiological range (Figure 1 highlights the physiology of the incretin hormones after a meal and the mode of action of DPP-4 inhibitors ( Figure 1 DPP-4 inhibitors have become an increasingly firmly established class of oral antidiabetic agents for the treatment of type 2 diabetes