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These challenges can lead to early generic entry if successful, but so far, no court rulings have cleared the way for generics in the U.S

Randall VA, Julie Thornton M, Hamada K, Messenger AG

The 23andMe Research Institute paper published in Nature on April 8, 2026 (Su et al., n 28,000 GLP-1RA users) identified a missense variant in the GLP-1 receptor gene, rs10305420, associated with an additional -0.76 kg of weight loss per copy of the effect allele on GLP-1 monotherapy

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These therapies are often part of performance medicine or recovery protocols for athletes and aging individuals seeking to preserve physical function

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