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In sensitivity analyses removing the only trial restricted to patients with an acute coronary syndrome (ELIXA), all benefits marginally increased, including the outcome of worsening of kidney function, based on eGFR change (HR = 0.82

Vision loss: NAION A 2024 study published in JAMA Ophthalmology found a significantly elevated risk of non-arteritic anterior ischemic optic neuropathy (NAION), a form of vision loss caused by reduced blood flow to the optic nerve, in people taking semaglutide

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Protein Synthesis Research IGF-1 LR3 regulates pathways responsible for cellular protein synthesis