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Taking 1 mL working solution as an example, add 100 L DMSO stock solution ( 20.8 mg/mL ) to 400 L PEG300 , and mix evenly

Engineered solely for preclinical investigations, each batch of Dihexa undergoes a comprehensive quality assessment and includes complete documentation, including a Certificate of Analysis (COA), purity data, and structural verification

While gastrointestinal side effects were common, they were mostly not acute

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The pharmacokinetics were compatible with a two-compartment model with a first-order distribution and elimination rate, and pharmacokinetic parameters were not different between the two doses, except for the elimination half-life

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