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Patent No EP3204045B1

C., & Simon, J

Hypoxia also has a role in promoting the expression of prooxidant enzymes such as myeloperoxidase (MPO) and inducible nitric oxide synthase (iNOS) in human uterine fibroid cells, leading to decreased apoptosis [7,34]

The link between OS and DNA damage was further suggested by elevated measurements of the respective biomarkers by Samarawickrema et al (2008), who studied the effects of low-grade long-term exposure to environmental and occupational OPCs [10]