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Iron deficiency-induce Fe-S synthesis disorders affect the voltage-dependent anion channel in the mitochondrial membrane, interferes with the overall stability of mitochondria, and induces apoptosis [292]
Ussing chamber analysis Cyclic AMP-activated CFTR chloride channel activity of dBCi cell monolayers was measured using a Ussing chamber as previously described 34
Among the existing system Xc inhibitors, erastin, a potent metabolically stable small molecule, has emerged as a therapeutic strategy to trigger cancer cell ferroptosis and has huge prospects for in vivo and in vitro applications (Wang et al
When used alongside chemotherapy agents, glutathione may exert cytoprotective effects that reduce treatment-related toxicity