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Research suggests it encourages the breakdown of stored fat without significantly affecting blood sugar or acting through the IGF-1 pathway

Lack of patient education or awareness: Many patients are unaware of how these medications work, how to manage side effects, or how to navigate the complexities of insurance coverage

During shortages of Wegovy, Ozempic, Mounjaro, and Zepbound, the FDA exercised temporary enforcement discretion , allowing compounding pharmacies to help meet patient demand. Once manufacturing stabilized: Semaglutide injection products were removed from the FDA Drug Shortage List Tirzepatide injection products were formally declared resolved Compounding reverted to pre-shortage federal and state limits Broad, shortage-based compounding is no longer allowed in 2026

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