A series of trials in populations with T2D will also be undertaken
Early trial data suggests retatrutide may lead to greater average weight loss than tirzepatide because it works on three pathways instead of two
The Right Fit Members at or near goal weight optimizing body composition Patients who tolerated standard GLP-1 dosing poorly but want the metabolic benefit Members layering the protocol into a longevity, recovery, or hormone strategy Not Appropriate For Patients with significant weight to lose who would be better served by a standard GLP-1 protocol Personal or family history of medullary thyroid carcinoma or MEN 2 Pregnancy, breastfeeding, or planning pregnancy What to Expect What to Expect Microdosing is measured in composition, energy, and how you feel not weekly weigh-ins
For the estimated 70% of eligible adults who have never filled a GLP-1 prescription, this is a meaningful change in what the treatment landscape looks like
WOMAC Pain Scores The trial assessed knee osteoarthritis pain using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) , a validated instrument widely used in orthopedic and rheumatologic research
Compounded versions of both range from $100-$500 per month