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Recently, two mechanisms involved in the gut-brain axis have attracted increasing attention due to their role in the pathogenesis and progression of PD, namely, disruption of the composition of microorganisms living in the intestine (intestinal microbiome) and dysfunction of enteroendocrine cells, accompanied by impaired signaling through the GLP-1R [60]

Treatment with glucagon-like peptide-1 receptor agonists and incidence of dementia: Data from pooled double-blind randomized controlled trials and nationwide disease and prescription registers

doi: 10.1001/JAMACARDIO.2021.3079 154

SOURCE Pendulum Therapeutics

ASCO is supported by its affiliate organization, the Conquer Cancer Foundation

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