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Winfrey started taking GLP-1 medication in 2023, then took a one-year break from 2024 to 2025

Others build comprehensive programs that integrate nutrition coaching, behavioral therapy, and exercise physiology

This is a potentially dangerous condition called hypoglycemia unawareness

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While this expanded, off-label use reflects the clinical effectiveness of these drugs for weight management, it also highlights the importance of appropriate patient selection and medical oversight