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Extended Timeline Support Establish funding mechanisms that support long-term investigation, allowing researchers to follow promising leads even when they diverge from original proposals

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In the context of wet age-related macular degeneration (AMD), geniposide (GEN), a GLP-1RA, is found to downregulate HB-EGF (heparin-binding epidermal growth factor) secretion from retinal pigment epithelium (RPE) cells under hypoxic conditions through the miR-145-5p/NF-B signaling axis

Oliveira ResendeCPedroso BetarelliRRabeloSSResende ChavesBRodriguez-GilJEZangeronimoMG