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doi: 10.3390/molecules24010009 84 WangWLiuWFidlerTWangYTangYWoodsBet al

Notably, the depletion of anti-HMGB1 neutralizing antibody or arginine catabolism enzyme (AGRE) mitigates macrophage inflammatory responses, suggesting that restricting HMGB1 expression may be a potential approach for managing macrophage inflammation (103, 104)