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[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Sim R, Guerci B, Schernthaner G, Gallwitz B, Rosas-Guzman J, Dotta F, et al

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In its discovery-to-proof-of-concept work, it activated both receptors in vitro , improved glucose-dependent insulin secretion and glucose tolerance in animals, and in early human studies lowered fasting glucose and body weight

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