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During lead optimization, less-sensitive cell assays are valuable for distinguishing the contributions of affinity and efficacy in the cellular response to an agonist ( 29 )

Intramuscular Administration When used intramuscularly, ME 12 Injection should not be repeatedly injected at the same place

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MT-II is investigated as a melanocortin receptor agonist (primarily MC1R/MC4R ) for studies spanning melanogenesis , UV/photobiology , energy balance , and neuroendocrine signaling

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10.1016/j.bbrc.2016.05.086 26 HeY.AoN.YangJ.WangX.JinS.DuJ