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A previous study demonstrated that the circadian transcription factor NFIL3, which controls the expression of circadian-clock genes, may be a crucial molecule in the influence of the gut microbiota on host lipid metabolism and body composition [56]

and Mareel, M.M., 1999

formulated PEG- curcumin- gold nanoparticle (PEG- cur- Au NP) and used it as a near-infrared photothermal agent, it was found that when this is used in combination with 808-nm diode laser irradiation, a sizeable reduction in the volume of the tumor was seen in- vivo , with no adverse effects on the animal's well-being [266]

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