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Recent regulatory milestones December 11, 2025: Eli Lilly released TRIUMPH-4 topline results (obesity + knee osteoarthritis)

2013 Jun

Keep in mind that TDEE is an estimate , not an exact science

The STEP clinical trials of semaglutide showed average weight reductions of roughly 12 to 15 percent of starting body weight over 68 weeks, while the SURMOUNT trials of tirzepatide showed slightly greater average weight loss, with reductions of roughly 18 to 22 percent of starting body weight at the highest doses

For a subset of vulnerable users, these medications aren't just a weight loss tool, but a powerful new way to reinforce disordered eating

medical director at the gynecological health company Daye, told Newsweek