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1, 6 July 2021, article 109336, www.sciencedirect.com/science/article/pii/S2211124721007129

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Early phase 2 clinical trial data also suggest a possible contribution to increased energy expenditure, though this effect has not yet been definitively confirmed as a major contributor to weight loss in humans and remains an area of ongoing investigation

Tirzepatide activates both GLP-1 and GIP receptors and may produce stronger results for some patients

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