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The primary causes include reduced caloric intake, electrolyte imbalances, blood sugar fluctuations, and metabolic adaptation to rapid weight loss

Prins, PhD, the Michael Reese Endowed Professor in the Departments of Urology, Physiology and Biophysics, and Pathology at the University of Illinois at Chicago (UIC) as well as co-director of the Prostate Cancer Research Program at the UIC Cancer Center reviewed several top candidate papers, settling on two from her journal

Being overweight, even severely overweight, typically does not qualify

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Its also required for healthy DNA methylation to prevent cancer, Alzheimers disease, and during pregnancy

Its a good option for people with PCOS who dont need to lose weight, says Ponder