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Treatment Plan: If youre a good candidate, theyll offer a single shot or a "loading course" a series of injections over a few weeks followed by regular maintenance top-ups

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Thus, in response to a sigmoidal gradient, in which the first derivative is symmetric around the gradient's midpoint, the pulsatile response is stronger in the first half, up to the maximal first derivative point, and decreases thereafter (Fig 2B)

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Avoid the belly button itself and any bruised or irritated skin