It has been suggested that the KD may also induce carnitine deficiency due to the high fat content 7
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Common causes include: injecting air into the vial during mixing, shaking instead of gently swirling, or using non-sterile bacteriostatic water
Cellular experiments further confirmed that silencing SIRT3 expression significantly promoted hypoxia- and doxorubicin (DOX)-induced cardiomyocyte apoptosis and lactate dehydrogenase (LDH) release, upregulated SOD2 expression and increased ROS release, inhibited Opa1, PINK1, and Parkin protein expression, and significantly increased Drp1, LC3- II, and p62 expression, suggesting that short-term aerobic exercise mediates SIRT3 protection against aging myocardial injury (Zhao D
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Antioxid (Basel) 11(5):943 Xie J, Yao Y, Yang C, Liu W, Zhou X, Zhang M (2022) Erythrocyte immune system: beyond the gas transporter