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If changing from an antipsychotic with high metabolic risk is not feasible, augmenting the antipsychotic with low or medium doses of aripiprazole (515 mg/day) can help

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La semaglutida ( Ozempic , desarrollada por Novo Nordisk) marc un nuevo avance al poseer una vida media de aproximadamente 165 horas, lo que permite una sola aplicacin semanal

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The tight junctions are formed by transmembrane proteins such as claudins, occludins, and JAMs, which are linked to cytosolic adapter proteins like ZO-1 and ZO-2, providing structural connections to the cytoskeleton (Kadry et al., 2020)