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The Overlapping Biology of Addiction and Obesity Research shows SUDs share biological and psychological similarities with overeating and obesity, with both involving dysregulation of the brains reward system (Srinivasan et al., 2025)

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Both types of hypogonadism can impact sperm count and cause other abnormalities in semen resulting in compromised fertility

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However, the use of oxygen within the body increases the energy available for use by its cells 20-fold, and aerobic metabolism allowed an explosion of development within the animal kingdom leading the great diversity of organisms that we see today

A fund from Mitsubishi Tanabe Pharma Corporation was partly used for recruitment of 12 healthy controls