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However, patients with severe liver disease should use this medication with extreme caution and regular monitoring

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It also has a real downside: roughly 40 percent of patients in the clinical trials reported nausea, with a meaningful number needing anti-nausea medication or stopping treatment because of it

Other proposed mechanisms of mitochondrial damage that could result in statin-induced liver injury include inhibition of the respiratory chain (i.e., complexes I, II, and III) and the release of calcium (Fig

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Tracking body composition, metabolic markers, and physical function can help distinguish healthy weight loss from unwanted muscle loss and guide adjustments over time