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This is an important reminder that Retatrutide side effects should not be reduced to gastrointestinal symptoms alone

The most frequent adverse effects are gastrointestinal and dose-related: Nausea, vomiting, diarrhoea, constipation, and abdominal discomfort - Typically worst during dose escalation and often resolve or attenuate with continued treatment and slower titration

They are also administered at different doses and last for different durations

Phase Early escalation Weeks Weeks 5-8 Weekly Dose 2 mg Notes First step up

Among the therapies evaluated, semaglutide 2.4 mg once weekly delivered the greatest reduction in body mass index (BMI) in adolescents with obesity

Willard, J.D