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Starting at 0.25 mg keeps side effects minimal for most peoplestudies show only 510% of patients report moderate nausea at this dose compared to 2030% at higher doses

However, researchers repeatedly recognize these potential effects: Lower glucose production in the liver Anti-inflammatory effects Anticancer effects Metformin is a weak complex I inhibitor (a part of the mitochondria), so it might activate stress responses that fight off disease

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