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No entanto, eles devem ser administrados com cautela devido ao risco potencial de hipoglicemia e ganho de peso, o que limita seu uso em pacientes com obesidade (ANTUNES et al., 2021) No entanto, o uso de sulfonilurias est associado a um risco maior de hipoglicemia, especialmente em pacientes idosos ou com insuficincia renal

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Li Y, Chigurupati S, Holloway H, et al

Compounded formulations also avoid the patent monopoly that protects brand-name drugs

Heterogeneity in the analyses vs active comparators could be attributed to differences in efficacy between the two GLP-1 RAs comparators (dulaglutide and semaglutide) or to differences in background glucose-lowering therapy between the two trials with basal insulin

Complete your titration with weekly dosing, then consider split dosing if side effects remain problematic at your target maintenance dose