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Furthermore, studies have reported an aberrant activation of NRF2, a key antioxidant transcription factor involved in the regulation of critical antioxidants including glutathione, SOD, and CAT, leading to reduced antioxidant capacity (Davinelli et al., 2025) In ASD children, the oxidative stress is not only higher, but it manifests in a complicated new pattern concerning different types of ROS and antioxidants (Hirayama et al., 2020)

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Cold atmospheric plasma induces the curing mechanism of diabetic wounds by regulating the oxidative stress mediators iNOS and NO, the pyroptotic mediators NLRP-3, caspase-1 and IL-1 and the angiogenesis mediators VEGF and Ang-1

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