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Activation of GLP-1 Receptors in the Central Nervous System Beyond the digestive tract, GLP-1 receptors are also present in the central nervous system, including areas of the brain that regulate appetite and nausea

Maruyama and A

The results are in for the REDEFINE 4 clinical trial, which was a major head-to-head study comparing Novo Nordisk's CagriSema against Eli Lilly's Zepbound (tirzepatide)

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Originally designed to treat type-2 diabetes, it belongs to the class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1 RA) and gastric inhibitory polypeptide receptor agonists (GIP-RA)

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