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As expected, the protein expressions of cleaved caspase 3 and cleaved PARP, two indicators of apoptosis, and the protein expressions of Smad3 and TGF-, two indicators of fibrosis, were highest in group 3 and lowest in groups 1 and 2, and significantly higher in group 4 than in group 5, but no difference between groups 1 and 2 (Fig

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Many patients notice reduced appetite and early weight loss within the first month, with steady progress over several months

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Genet., 101 : 89-98