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The impact of cysteine deprivation on TNBC encompasses various aspects, including proliferation, resistance to chemotherapy and antitumor properties

On the regulatory side: neither BPC-157 nor TB-500 is approved by the FDA or EMA for human use

doi:10.1056/NEJMoa2410659

Some studies show that when combined with a calorie-controlled diet, Alpha lipoic acid supplementation may enhance weight loss

Furthermore, glutathione deficiency may result in loss of immune tolerance and the increase of oxidative stress, causing a further development of the disease

Despite the potential benefits of dietary interventions, their clinical translation remains hindered by several bottlenecks