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We are using the mouse as a model organism to study the roles of these regulatory factors during vertebrate development, focusing on skeletal tissues
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Unlike other CNS disorders, cerebral ischemias lactylation dysregulation is uniquely driven by acute hypoxia-induced mitochondrial dysfunction and ANLS collapsekey pathogenic targets include LCP1 and ARF1 lactylation, which specifically mediate calcium overload and mitochondrial transfer impairment
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91:346770 [PubMed] [Google Scholar] 29.Repka T, Hebbel RP
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