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doi: 10.1056/NEJMoa1411892 124 ButlerAEJansonJBonner-WeirSRitzelRRizzaRAButlerPC

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Furthermore, GLP-1 acts on central nervous system receptors in the paraventricular nucleus of the hypothalamus and the central nucleus of the amygdala to promote satiety and reduce food intake (Turton et al 1996) (Fig

The most recently approved type, tirzepatide [archived link], is called a dual agonist because it mimics the effects of two gut hormones, GLP-1 and GIP (glucose-dependent insulinotropic polypeptide)

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But some feedback also mentions common problems, like treatment discontinuation