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Intriguingly, metformin has been shown to act on anti-inflammatory pathways to prevent/reduce the progression of these neural degenerative diseases

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Similar content being viewed by others Introduction Obesity is a major chronic disease that continues to increase in prevalence worldwide and constitutes a key risk factor for development and progression of numerous related diseases including hypertension, dyslipidaemia and type 2 diabetes 1

3 Overall, 17% of children with ASD were found to demonstrate a unique pattern of acyl-carnitine abnormalities that were similar to the acyl-carnitine abnormalities found in the rodent PPA model of ASD

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