A possible biological interpretation of these findings is that improving insulin resistance and reducing chronic hyperinsulinemia may attenuate part of the proliferative stimulus linked to the insulin/IGF-1 axis
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Mandal PK, Schneider M, Klle P, Kuhlencordt P, Frster H, Beck H, Bornkamm GW, Conrad M (2010) Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation
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