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Although no specific definition is used in the literature for clinically significant WR, it can be defined as progressive weight gain after a successful initial weight loss [1]
In hEDS-associated neuropathic POTS where partial sympathetic denervation of the lower extremity vasculature produces blunted vasoconstriction, blood already pools in peripheral capacitance vessels on standing, stroke volume is structurally reduced, and the sympathetic nervous system is already operating near its compensation ceiling the additional vasodilatory and chronotropic load imposed by chronic dual incretin receptor agonism may have limited physiological reserve to absorb it
Common experiences: Noticeably decreased appetite Early fullness Mild nausea Less interest in snacking What your medical weight loss plan includes: Starting at the lowest effective dose Hydration goal: 100 oz/day Protein goal: 100-150g daily Constipation prevention plan (may include fiber, magnesium glycinate, hydration) Week 1 priority: Learning to listen to your body without skipping essential nutrition
Always receive the injection under professional supervision
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